The MYRTUS project is paving the way for a more secure, sustainable, and efficient computing ecosystem by leveraging RISC-V and open-source hardware. In this session, we will explore how MYRTUS addresses challenges in trustworthy computing and energy-efficient architectures, focusing on its impact on edge AI, security, and sustainability. Join us to discover how this project shapes the future of hardware-software co-design for next-generation applications. (MYRTUS is funded by the European Union, by grant No. 101135183)